Under this new regimen, he experienced significant side effects including diarrhea, nausea, skin eruptions, and', within severalweeks, significant hair loss. His colon cancer responded to the new chemo regimen, and his CEA dropped to 396ng/ml in 4 weeks (February 2010) and 359n9/ml in 2 months (March 2010). The patient's CT after 3 months of chemo (April 2010) showed significant reduction of tumor size ( < | / lO of the volume at the time of discovery) and widespread calcification. His fucoidan regimen was changed to a 50/50 mix of Fucus vesiculous and Undaria pinnatifida at the end of March 2010. The same chemo protocol continued and his CEA dropped to l2.4Oby f uly 2010 and his CT at the end of July also showed reductions in tumor size and count. As of f uly 3l ,2OlO, the patient is still on the same protocol. LaserCap Treatment Hoping to stop the patient's hair loss, in April 2010 Drs. Tseng-Kuo and I-Sen Shiao had started the patient on LaserCap treatment. LaserCap is a portable low level laser therapy device containin 9224-65Onm 5mw laser diodes. The patient received 30-minute LaserCap treatments 2-3 times a week. By lune 2OlO, after 23 sessions (about 9 weeks of LaserCap therapy), the patient's hair loss had completely stopped.

 Under this new regimen, he experienced significant side effects including diarrhea, nausea, skin eruptions, and', within severalweeks, significant hair loss. His colon cancer responded to the new chemo regimen, and his CEA dropped to 396ng/ml in 4 weeks (February 2010) and 359n9/ml in 2 months (March 2010). The patient's CT after 3 months of chemo (April 2010) showed significant reduction of tumor size ( < | / lO of the volume at the time of discovery) and widespread calcification. His fucoidan regimen was changed to a 50/50 mix of Fucus vesiculous and Undaria pinnatifida at the end of March 2010. The same chemo protocol continued and his CEA dropped to l2.4Oby f uly 2010 and his CT at the end of July also showed reductions in tumor size and count. As of f uly 3l ,2OlO, the patient is still on the same protocol. LaserCap Treatment Hoping to stop the patient's hair loss, in April 2010 Drs. Tseng-Kuo and I-Sen Shiao had started the patient on LaserCap treatment. LaserCap is a portable low level laser therapy device containin 9224-65Onm 5mw laser diodes. The patient received 30-minute LaserCap treatments 2-3 times a week. By lune 2OlO, after 23 sessions (about 9 weeks of LaserCap therapy), the patient's hair loss had completely stopped.

 He had also regained his lost hair and may have had a higher hair density than he did prior to chemotherapy (Figure 2). The patient did not use minoxidil, because it irritated his already compromised skin (from cetuximab) Discussion Few dermatologic conditions carry as much emotional distress as chemotherapy-induced alopecia. lt is psychologically daunting as it constantly reminds the patient of the disease, and patients have even refused possibly palliative or lifesaving drugs because they could not accept the temporary or prolonged baldness. In this patient's case, once his hair loss ceased, his family members noticed a change in his mood from being depressed to being much more relaxed. In his words, "lt was very depressing to see hair all over my pillow when I got up every morning and to watch gobs of hair falling off each time I combed my hair. 

Now I feel bad for other cheino recipients who do not have access to the LaserCap." As far as we know, this is the first reported case of successful treatment of hair loss induced by chemotherapy while the patient is undergoing active chemotherapy under the same regimen. However, this is an anecdotal case and controlled studies must be done to determine if low level laser therapy is really useful in chemotherapy-induced alopecia, or if such success is only possible against certain chemotherapeutic agents or influenced by the patient's age, gender, and degree of hair loss. We must also determine if low level Iaser therapy was solely responsible for the success or if any alternative therapies this patient received, such as fucoidan, fermented wheat germ extract, and IV Vitamin C, also played a role. Nevertheless, we hope this case report will lead to a new direction in finding treatment for chemotherapy-induced alopecia and bring hope to the millions suffering from this heart-wrenching condition